The relationship between heart failure with preserved ejection fraction and cardiovascular risk factors

Written by Szabados Csongor, Buzogány Jázmin, Orbán Viktor, Mihály Katinka oh., Ambarus Andrea oh., Mezei Katalin oh., Incze Sándor

Background: Heart failure (HF) represents a major health concern with a severe outcome despite modern therapies. In more than 50% of cases left ventricular (LV) systolic function is preserved. Methods: 19 patients (7 male,12 female) fulfilling the criteria for heart failure with preserved ejection fraction (HFPEF) (EF>50%), underwent 2D echocardiography, metabolic and clinical evaluation. Diastolic function was characterized as delayed relaxation pattern, pseudo normal or restrictive. Results: Mean age of the patients was 62 ± 13 years. 14 patients had delayed relaxation pattern, 2 patients had pseudonormal pattern, and 3 patients had restrictive. There were no significant association regarding the severity of diastolic dysfunction with glucose levels, lipids and systolic or diastolic blood pressure values. 4 patients had high NYHA class heart failure, and 3 pts from this group associated restrictive pattern and atrial fibrillation. Conclusions: The most common diastolic dysfunction was the delayed relaxation pattern. Higher NYHA class was associated with restrictive pattern and with the presence of atrial fibrillation.

 

Keywords: heart failure, cardiovascular risk factors, diastolic function


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