One of my early dreams as a young scientist engaged in biomedical research was to visit the famous Institute of Professor Hans Selye in Montreal and even to work with him. Although I did not know him personally, for me he was the scientist who incarnated creativity and originality. I knew his basic discoveries and his concept of stress, the exhaustion of the organism, pluricausal diseases, and the adaptation syndrome. I was particularly excited because the focus of my interest was very close to that of the research topics in the Selye Institute.