The microcirculatory reactivity in primary and scleroderma-caused secondary Raynaud’s phenomenon

Written by Imre Mihály, Orbán Enikő Réka, Balogh Zsolt Elek, Makó Katalin, Puskás Attila, Brassai Zoltán

Raynaud’s phenomenon was described at first as an increase in sympathetic tonus, than as the failure of finger arteries. The authors in this work present the differences appeared in microcirculatory reactivity, between these two entities. The 33 patients (9 healthy, 10 primary Raynaud’s and 14 scleroderma-caused secondary Raynaud’s phenomenon) were submitted to several tests, like post occlusive reactive hyperemia test, psycho-physiological reactivity test, or cold test. The peak flow was pathologically reduced in the scleroderma group (ps/h=0,0073), but the time to peak, the psycho-physiological reactivity test, and the cold test turned to be pathologic in the primary group (TTP: pp/h=0,0009, pp/s=0,03, CT: pp/s=0,0035). The result of this study underlines the role of this method in the early diagnosis and differential diagnosis of Raynaud’s phenomenon, and also provides complementary data in understanding its physiopathology.

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