Introduction: In developed countries the frequency of endometrial cancer is rising. The screening cannot be realized because there is no noninvasive method sensible and specific enough that can be used on a large scale. In spite all of these when a suspicion exists, exclusion is obligatory. In our clinic dilatation and curettage (D&C) is the standart method for endometrial biopsy. Objective: Our aim was to study those patients who underwent biopsic dilatation and curettage in the I. Obstetrics and Gynecology Clinic of Tg.Mureş. Material and methods: In most cases the biopsy was done for abnormal uterine bleeding (69%). The most frequent histopathologic diagnosis was the endometrial polyp without atypia (28%). We diagnosed 6 cases (1,2%) of complex endometrial hyperplasia, 15 cases (3%) of endometrial adenocarcinoma and one case (0,2%) of undifferentiated carcinoma. 81% of the malignant cases were detected in postmenopause; in patients in postmenopause presenting metrorrhagia malignant lesions were detected in 11,5%. Conclusions: In our group the frequency of premalignant and malignant lesions was congruent with the international publications. Dilatation and curettage is a relatively expensive intervention, which, mostly in postmenopause, has complications being unpleasant and traumatic for patients; all of these justify and make necessary the study of other, less invasive biopsic methods.
Keywords: endometrium, biopsy, dilatation and curettage.